Nudel colocalizes with Cdk5 in axonal growth cones and cell bodies of cultured embryonic hippocampal neurons. Lukas, V. After transfection for 36 h, HEKT cells were collected. Their dissociation rates are therefore negligible during the assays. Such poleward congression was also observed in cells from anaphase Fig. We also thank X.
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Mutually exclusive cytoplasmic dynein regulation by NudE-Lis1 and dynactin.
Such deletion completely disrupted Nudel-Lis1 interaction Fig. A decade of CDK5. For clues at the molecular level, we performed coimmunoprecipitation to check interactions between Nudel, Lis1, and dynein. Niethammer, M. Typical cells in interphase panels 1 and 2 and M phase panels 3 and 4 are shown.